{"id":1204,"date":"2011-11-10T11:00:00","date_gmt":"2011-11-10T11:00:00","guid":{"rendered":"http:\/\/www.emlitofnote.com\/?p=1204"},"modified":"2016-08-01T08:58:56","modified_gmt":"2016-08-01T15:58:56","slug":"ethanol-miracle-drug-for-stroke","status":"publish","type":"post","link":"https:\/\/www.emlitofnote.com\/?p=1204","title":{"rendered":"Ethanol &#8211; Miracle Drug (For Stroke)"},"content":{"rendered":"<div>From China, in Stroke, an animal model (poor rats, as usual) of MCA ischemia, collagenase-induced ICH, and post-TPA ICH. &nbsp;Rats received either 0.5 mg\/kg, 1.0 mg\/kg, or 1.5 mg\/kg ethanol after two hours of MCA occlusion. &nbsp;Performance on various foot, balance, and parallel behavioral testing significantly favored the ethanol treatment group with initial and sustained reduction in errors as compared to the no-treatment group.<\/p>\n<p>No difference was found between groups in induced ICH volume, and in their (small) series, no increase in ICH after TPA administration. &nbsp;A transient increase in expression of hypoxia-inducible factor 1-alpha favoring ethanol was seen at 3 hours after reperfusion, gone by 24 hours.<\/p>\n<p>I <i>cannot<\/i> <i>wait<\/i> to see the day where we give IV ethanol for acute stroke.<\/p>\n<p>&#8220;Beer, the cause and solution to all the world&#8217;s problems.&#8221;<\/p>\n<p>&#8220;Neuroprotective Effect of Acute Ethanol Administration in a Rat With Transient Cerebral Ischemia&#8221;<\/p><\/div>\n<div><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22052512\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/22052512<\/a><\/div>\n\n<div class=\"twitter-share\"><a href=\"https:\/\/twitter.com\/intent\/tweet?via=emlitofnote\" class=\"twitter-share-button\">Tweet<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>From China, in Stroke, an animal model (poor rats, as usual) of MCA ischemia, collagenase-induced ICH, and post-TPA ICH. &nbsp;Rats received either 0.5 mg\/kg, 1.0 mg\/kg, or 1.5 mg\/kg ethanol after two hours of MCA occlusion. &nbsp;Performance on various foot, balance, and parallel behavioral testing significantly favored the ethanol treatment group with initial and sustained &hellip; <a href=\"https:\/\/www.emlitofnote.com\/?p=1204\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Ethanol &#8211; Miracle Drug (For Stroke)&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_feature_clip_id":0,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[14,15],"tags":[],"class_list":["post-1204","post","type-post","status-publish","format-standard","hentry","category-neurology","category-stroke"],"jetpack_publicize_connections":[],"jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p7KesJ-jq","jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=\/wp\/v2\/posts\/1204","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1204"}],"version-history":[{"count":1,"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=\/wp\/v2\/posts\/1204\/revisions"}],"predecessor-version":[{"id":2943,"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=\/wp\/v2\/posts\/1204\/revisions\/2943"}],"wp:attachment":[{"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1204"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1204"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1204"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}