{"id":3268,"date":"2015-06-17T15:00:00","date_gmt":"2015-06-17T15:00:00","guid":{"rendered":"http:\/\/www.emlitofnote.com\/?p=3268"},"modified":"2015-06-17T15:00:00","modified_gmt":"2015-06-17T15:00:00","slug":"can-you-diagnose-pe-with-a-walk-test","status":"publish","type":"post","link":"https:\/\/www.emlitofnote.com\/?p=3268","title":{"rendered":"Can You Diagnose PE With a Walk Test?"},"content":{"rendered":"<p>So, no.<\/p>\n<p>You can stop reading now, if that\u2019s enough information to satisfy your curiosity. &nbsp;There is, however, a little more to it.<\/p>\n<p>These authors describe a prospective evaluation of 114 Emergency Department patients with either suspected or confirmed acute pulmonary embolism. &nbsp;Patients were enrolled by convenience selection during the hours research assistants were in the ED. &nbsp;Each enrolled patient underwent a 3-minute walk test while research assistants measured changes in heart rate, respiratory rate, and oxygen saturation.<\/p>\n<p>In short, ambulation induced significant changes in heart rate and oxygen saturation between those who did, and did not, have pulmonary embolism. &nbsp;A change in heart rate of 10 bpm gave a sensitivity of 97% (95% CI 83 to 99%) and specificity of 31% (95% CI 22-42%), while a drop in O2 saturation of 2% gave a sensitivity of 80% (95% CI 63 to 91%) and specificity of 39% (95% CI 30 to 50%). &nbsp;Obviously, these test characteristics are poor \u2013 excepting, perhaps, a potentially useful negative likelihood ratio, particularly when both variables are utilized. &nbsp;However, there are also serious issues with their gold-standard for diagnosis of pulmonary embolism \u2013 with nearly 30% of their cohort undergoing ventilation\/perfusion scans.<\/p>\n<p>I appreciate these authors\u2019 attempt to describe the test characteristics of, essentially, a free, non-invasive physiologic stress \u2013 and, even if the current data does not support routine use, it\u2019s probably worth continuing to explore.<\/p>\n<p>\u201cAmbulatory vital signs in the workup of pulmonary embolism using a standardized 3-minute walk test\u201d<br \/><a href=\"http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26034913\">http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/26034913<\/a><\/p>\n\n<div class=\"twitter-share\"><a href=\"https:\/\/twitter.com\/intent\/tweet?via=emlitofnote\" class=\"twitter-share-button\">Tweet<\/a><\/div>\n","protected":false},"excerpt":{"rendered":"<p>So, no. You can stop reading now, if that\u2019s enough information to satisfy your curiosity. &nbsp;There is, however, a little more to it. These authors describe a prospective evaluation of 114 Emergency Department patients with either suspected or confirmed acute pulmonary embolism. &nbsp;Patients were enrolled by convenience selection during the hours research assistants were in &hellip; <a href=\"https:\/\/www.emlitofnote.com\/?p=3268\" class=\"more-link\">Continue reading<span class=\"screen-reader-text\"> &#8220;Can You Diagnose PE With a Walk Test?&#8221;<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"nf_dc_page":"","_jetpack_newsletter_access":"","_jetpack_dont_email_post_to_subs":false,"_jetpack_newsletter_tier_id":0,"_jetpack_memberships_contains_paywalled_content":false,"_jetpack_memberships_contains_paid_content":false,"footnotes":"","jetpack_publicize_message":"","jetpack_publicize_feature_enabled":true,"jetpack_social_post_already_shared":true,"jetpack_social_options":{"image_generator_settings":{"template":"highway","default_image_id":0,"font":"","enabled":false},"version":2},"jetpack_post_was_ever_published":false},"categories":[4],"tags":[],"class_list":["post-3268","post","type-post","status-publish","format-standard","hentry","category-pulmonary-embolism"],"jetpack_publicize_connections":[],"jetpack_featured_media_url":"","jetpack_sharing_enabled":true,"jetpack_shortlink":"https:\/\/wp.me\/p7KesJ-QI","_links":{"self":[{"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=\/wp\/v2\/posts\/3268","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3268"}],"version-history":[{"count":0,"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=\/wp\/v2\/posts\/3268\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3268"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3268"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.emlitofnote.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3268"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}